State-of-the-art Fluorescence
Time resolved fluorescence spectroscopy
Measurement of the time dependence of fluorescence emission. Extremely sensitive to molecular environment/interactions.
Facilities
Tuneable excitation
Picosecond resolution using single photon counting technique
Applications
Similar to those suited to Raman, infra-red and steady state fluorescence spectroscopy. Often, however, time resolved techniques provide the most sensitive probe of material structure.
Single molecule spectroscopy
The ultimate in sensitivity - the ability to detect one fluorescent molecule
Facilities
Fluorescence correlation spectroscopy, resonance energy transfer measurements, total internal reflection fluorescence spectroscopy for molecules on surfaces
Avacta can also provide design expertise for new SMF instrumentation.
Applications
Detection of analytes at sub-nanomolar concentration; Studies of heterogeneity in molecular structure, dynamics and interactions.